Effects of Prenatal Hormone Treatment on Mental Abilities

  • Heino F. L. Meyer-Bahlburg
  • Anke A. Ehrhardt
Part of the Perspectives in Sexuality book series (Persp. Sex.)


The research on the influence of sex hormones on the developing brain focuses on two aspects: one is the influence on the whole brain, learning ability, and intelligence; the other is the influence on specific brain systems, especially those that relate to sex-dimorphic behavior. We are currently conducting a study on the effects of various hormones on both aspects but will limit this report to the effects of a synthetic steroid hormone, medroxyprogesterone acetate (MPA), on general mental abilities.


Medroxyprogesterone Acetate Mental Ability General Mental Ability Habitual Abortion Toxemic Pregnancy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bailey, M.A. (1963). Toxemia of pregnancy: cognitive and emotional effects in children from consistent and non-consistent environments. Ph.D. thesis. Xerox University Microfilms, Ann Arbor, Michigan.Google Scholar
  2. Cohen, J. (1957). A factor-analytically based rationale for the Wechsler Adult Intelligence Scale. J. Consult. Psychol. 21: 451–457.CrossRefGoogle Scholar
  3. Cohen, J. (1959). The factorial structure of the WISC at ages 7–6, 10–6, 13–6. J. Consult. Psychol. 23: 285–299.CrossRefGoogle Scholar
  4. The Collaborative Perinatal Study of the National Institute of Neurological Diseases and Stroke. (1972). The Women and Their Pregnancies, W.B. Saunders, Philadelphia.Google Scholar
  5. Dalton, K. (1968). Ante-natal progesterone and intelligence. Brit. J. Psychiat. 114: 1377–1382.CrossRefGoogle Scholar
  6. Dalton, K. (1976). Prenatal progesterone and educational attainments. Brit. J. Psychiat. 129: 438–442.CrossRefGoogle Scholar
  7. Dobbing, J., and Sands, J. (1973). Quantitative growth and development of human brain. Arch. Dis. Child., 48: 757–767.CrossRefGoogle Scholar
  8. Ehrhardt, A.A., Grisanti, G.C., and Meyer-Bahlburg, H.F.L. (In press). Prenatal exposure to medroxyprogesterone acetate (MPA) in girls. Psychoneuroendocrinology.Google Scholar
  9. Ehrhardt, A.A., and Meyer-Bahlburg, H.F.L. (1977). Prenatal progestogen and gender-role behavior in childhood. Paper presented at the 34th Annual Meeting of the American Psychosomatic Society, Atlanta, Georgia, March 25–27, 1977.Google Scholar
  10. Ehrhardt, A.A., and Money, J. (1967). Progestin-induced hermaphroditism, IQ and psychosexual identity in a study of 10 girls. J. Sex Res. 3:83–100.CrossRefGoogle Scholar
  11. Meyer-Bahlburg, H.F.L., Grisanti, G.C., and Ehrhardt, A.A. (In press). Prenatal exposure to medroxyprogesterone acetate (MPA): behavioral effects in boys. Psychoneuroendocrinology.Google Scholar
  12. Reifenstein, E.C., Jr. (1958). Clinical use of 17 α-hydroxyprogesterone 17-η-caproate in habitual abortion. Annals New York Acad. Sci. 71: 762–786.CrossRefGoogle Scholar
  13. SRA Non-Verbal Form. (1947). Science Research Associates, Inc., Chicago, Illinois.Google Scholar
  14. U.S. Bureau of the Census. (1963). Methodology and scores of socioeconomic status. Working paper no. 15. Washington, D.C.Google Scholar
  15. Wechsler, D. (1974). Wechsler Intelligence Scale for Children-Revised. Psychological Corporation, New York.Google Scholar
  16. Zussman, J.U., Zussman, P.P., and Dalton, K. (1975). Post-pubertal effects of prenatal administration of progesterone. Paper presented at the meeting of the Society for Research in Child Development, Denver, Colorado, April 1975.Google Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Heino F. L. Meyer-Bahlburg
    • 1
  • Anke A. Ehrhardt
    • 1
  1. 1.USA

Personalised recommendations