Cancer in Inflammatory Bowel Disease: Risk Factors and Prospects for Early Detection
Chronic inflammation or irritation has been considered responsible for the development of various cancers in man, although the etiology and mechanisms associated with the development of the neoplastic state have never been clarified. Examples include achalasia and lye strictures with carcinoma of the esophagus, atrophic gastritis with carcinoma of the stomach, cholelithiasis with cancer of the gallbladder, tobacco and alcohol with cancers of the oral cavity, Clonorchis sinesis infestation with cholangiocarcinoma, Schistosoma haematobium infestation with cancer of the urinary bladder, mucosal ulcerative colitis with carcinoma of the colon, and Crohn’s disease with both carcinoma of the ileum and colon.
KeywordsInflammatory Bowel Disease Ulcerative Colitis Carcinoembryonic Antigen Atrophic Gastritis Rectal Mucosa
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