Advertisement

Familial Polyposis Coli

  • H. J. R. Bussey
  • Basil C. Morson
Part of the Sloan-Kettering Institute Cancer Series book series (SKICS)

Abstract

Although it is now 250 years since intestinal polyposis was first reported, probably not until 1847 was the first account given, by Corvisart, of what is now known as “familial polyposis coli.” Twelve years later, Chargelaigue described the disease in two patients, a 16-year-old girl and a man aged 21 years. Since then the main characteristics have been established by numerous other case reports. Harrison Cripps (1882) gave the first indication that polyposis coli might be familial when he diagnosed multiple rectal polyps in a brother and sister. Many similar observations since then have firmly established the inherited nature of the disease. A littler later, Handford (1890) appears to have been the first to notice the high incidence of associated carcinoma of the colon and rectum. This observation, also fully substantiated by many subsequent reports, has important consequences in the study of the etiology of intestinal cancer and gives polyposis coli an interest and value much greater than its rarity would seem to justify.

Keywords

Adenomatous Polyp Villous Adenoma Familial Polyposis Ileorectal Anastomosis Intestinal Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alm, T., and Licznerski, G., 1973, The intestinal polyposis, Clin. Gastroenterol. 2: 577–602.Google Scholar
  2. Birbeck, M. S. C., and Dukes, C. E., 1963, Electron microscopy of rectal neoplasms, Proc. R. Soc. Med. 56: 793–798.PubMedGoogle Scholar
  3. Bussey, H. J. R., 1975, Familial Polyposis Coli, Johns Hopkins University Press, Baltimore.Google Scholar
  4. Chargelaigue, A., 1859, Des polyps du rectum, Thesis, Paris.Google Scholar
  5. Corvisart, L., 1847, Hypertrophie partielle de la muqueuse intestinale, Bull. Soc. Anat. 22: 400.Google Scholar
  6. Cripps, W. H., 1882, Two cases of disseminated polypus of the rectum, Trans. Pathol. Soc. London 33: 165–168.Google Scholar
  7. Gardner, E. J., 1969, Gardner’s syndrome re-evaluated after twenty years, Proc. Utah Acad. 46: 111Google Scholar
  8. Gruenberg, J., and Mackman, S., 1972, Multiple lymphoid polyps in familial polyposis, Ann. Surg. 175: 552–554.PubMedCrossRefGoogle Scholar
  9. Handford, H., 1890, Disseminated polypi of the large intestine becoming malignant, Trans. Pathol. Soc. London 41: 133.Google Scholar
  10. Louw, J. H., 1968, Polypoid lesions of the large bowel in children with particular reference to benign lymphoid polyposis, Pediatr. Surg. 3: 195–209.CrossRefGoogle Scholar
  11. Lovett, E., 1976, Family studies in cancer of the colon and rectum, Brit. J. Surg. 63: 13–18.PubMedCrossRefGoogle Scholar
  12. Moertel, C. G., Hill, J. R., and Adson, M. A., 1970, The surgical management of multiple polyposis, Arch. Surg. 100: 521–526.PubMedCrossRefGoogle Scholar
  13. Morson, B. C., 1974, The polyp-cancer sequence in the large bowel, Proc. R. Soc. Med. 67: 451–457.PubMedGoogle Scholar
  14. Morson, B. C., and Bussey, H. J. R., 1970, Predisposing causes of intestinal cancer, in: Current Problems in Surgery, Year Book Medical Publishers, Chicago.Google Scholar
  15. Muto, T., Bussey, H. J. R., and Morson, B. C., 1975, The evolution of cancer of the colon and rectum, Cancer 36: 2251–2270.PubMedCrossRefGoogle Scholar
  16. Neel, J. V., 1954, Problems in the estimation of the frequency of uncommon inherited traits, Am. J. Hum. Genet. 6: 51.PubMedGoogle Scholar
  17. Pierce, E. R., 1968, Some genetic aspects of familial multiple polyposis of the colon in a kindred of 1,422 members, Dis. Colon Rectum 11: 321–329.PubMedCrossRefGoogle Scholar
  18. Reed, T. E., and Neel, J. V., 1955, A genetic study of multiple polyposis of the colon (with an appendix deriving a method of estimating relative fitness), Am. J. Hum. Genet. 7: 236–263.PubMedGoogle Scholar
  19. Schaupp, W. C., and Volpe, P. A., 1972, Management of diffuse colonic polyposis, Am. J. Surg. 124: 218–222.PubMedCrossRefGoogle Scholar
  20. Scully, R. E., 1970, Sex cord tumor with annular tubules: A distinctive ovarian tumor of the Peutz-Jeghers syndrome, Cancer 25: 1107–1121.PubMedCrossRefGoogle Scholar
  21. Smith, W. G., 1968, Familial multiple polyposis: Research tool for investigating the etiology of carcinoma of the colon? Dis. Colon Rectum 11: 17–31.PubMedCrossRefGoogle Scholar
  22. Turcot, J., Despres, J. P., and St. Pierre, F. 1959, Malignant tumors of the central nervous system associated with familial polyposis of the colon, Dis. Colon Rectum 2: 465–468.PubMedCrossRefGoogle Scholar
  23. Utsunomiya, J., and Nakamura, T., 1975, The occult osteomatous changes in the mandible in patients with familial polyposis coli, Br. J. Surg. 62: 45–51.PubMedCrossRefGoogle Scholar
  24. Vargish, T., Dawkins, H. G., Heise, E., and Myers, R. T., 1975, Serologic detection of persons at risk in familial polyposis coli, in: Surgical Forum Vol. 26, 61st Annual Congress, American College of Surgeons.Google Scholar
  25. Veale, A. M. O., 1958, Possible autosomal linkage in man, Nature (London) 182: 409–410.CrossRefGoogle Scholar
  26. Veale, A. M. O., 1965, Intestinal Polyposis, Eugenics Laboratory Memoirs, Series 40, Cambridge University Press, London.Google Scholar
  27. Veale, A. M. O., McColl, I., Bussey, H. J. R., and Morson, B. C., 1966, Juvenile polyposis coli, J. Med. Genet. 3: 5–16.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1978

Authors and Affiliations

  • H. J. R. Bussey
    • 1
  • Basil C. Morson
    • 1
  1. 1.St. Mark’s HospitalLondonEngland

Personalised recommendations