Eye Movements pp 105-126 | Cite as

The Role of the Brain Stem Reticular Formation in Eye Movement Control

  • Edward L. Keller


A previous review (Cohen and Henn, 1972b) has summarized the past work on oculomotor relations of the brain stem reticular formation including information from lesion studies, electrical stimulation, and field potential analysis. These studies as a whole support the hypothesis that this region of the reticular formation, and in particular the medial pontine reticular formation (PRF), is the location of the immediate supranuclear neural structures responsible for generating conjugate horizontal rapid eye movements (saccades and the quick-phase movements of nystagmus). This review will concentrate on the additional support for this view that has accumulated in the form of single-unit recordings in alert animals, electrophysiological studies of synaptic connections, and detailed neuroanatomical tracing techniques. In addition some new data on functional interconnections of the PRF with the superior colliculus (SC), a higher visual-motor control center also implicated in the generation of saccades, will be presented.


Superior Colliculus Reticular Formation Pontine Reticular Formation Abducens Nucleus Vestibular Nystagmus 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Edward L. Keller
    • 1
  1. 1.Department of Electrical Engineering and Computer Sciences and the Electronics Research LaboratoryUniversity of CaliforniaBerkeleyUSA

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