Chemical Attractants of the Rat Preputial Gland

  • Anthony M. Gawienowski


The interest in olfaction and the relationship to animal behavior has brought attention to the preputial and other glands as a source of chemical attractants. The molecules, synthesized by one animal, affect the physiology and behavior of another of the same species.


Dimethyl Disulfide Glyceryl Ether Testosterone Propionate Preputial Gland Olfactory Preference 


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  1. Bronson, F. H., and Caroom, D. 1971. Preputial gland of the male mouse: attractant function. J. Reprod. Fertil. 279–282.Google Scholar
  2. Bronson, F. H. 1974. Pheromonal influences on reproductive activities, pp. 344–365 in Birch, M. C. (ed.), Pheromones. Elsevier, New York.Google Scholar
  3. Brown, J. C., and Williams, J. D. 1972. The rodent preputial gland. Mammal Review 2: 105–147.CrossRefGoogle Scholar
  4. Carr, W. J., Loeb, L. S., and Wylie, N. R. 1966. Responses to feminine odors in normal and castrated male rats. J. Comp. Physiol. Psychol. 62: 336–338.PubMedCrossRefGoogle Scholar
  5. Carr, W. J., Krames, L., and Costanzo, D. J. 1970. Previous sexual experience and olfactory preference for novel versus original sex partners in rats. J. Comp. Physiol. Psychol. 71: 216–222.PubMedCrossRefGoogle Scholar
  6. Gawienowski, A. M., Orsulak, P. J., Stacewicz-Sapuntzakis, M., and Joseph, B. M. 1975. Presence of sex pheromone in preputial glands of male rats. J. Endocrinol. 67: 283–288.PubMedCrossRefGoogle Scholar
  7. Gawienowski, A. M., Orsulak, P. J., Stacewicz-Sapuntzakis, M., and Pratt, J. Jr. 1976. Attractant effect of female preputial gland extracts on the male rat. Psychoneuroendocrinol. 1: 411–418.CrossRefGoogle Scholar
  8. Gawienowski, A. M., and Stacewicz-Sapuntzakis, M. 1976b. Attraction of male rats to dimethyl disulfide and dimethyl sulfite, submitted for publication.Google Scholar
  9. Mykytowycz, R. 1974. Odor in the spacing behavior of mammals, pp. 327–343 in Birch, M. C. (ed.). Pheromones. Elsevier, New York.Google Scholar
  10. Orsulak, P. J., and Gawienowski, A. M. 1972. Olfactory preferences for the rat preputial gland. Biol. Reproduction 6: 219: 223.Google Scholar
  11. Sansone-Bazzano, G., Bazzano, G., Reisner, R. M., and Hamilton, J. G. 1972. The hormonal induction of alkyl glycerol, wax and alkyl acetate synthesis in the preputial gland of the mouse. Biochim. Biophys. Acta 260: 35–40.Google Scholar
  12. Singer, A. G., Agosta, W. C., O’Connell, R. J., Pfaffman, C., Bowen, D. V., and Field, F. H. 1976. Dimethyl disulfide: an attractant pheromone in hamster vaginal secretion. Science 191: 948–950.PubMedCrossRefGoogle Scholar
  13. Snyder, F., Wykle, R. L., and Malone, B. 1969. A new metabolic pathway: biosynthesis of alkyl ether bonds from glyceraldehyde-3-phosphate and fatty alcohols by microsomal enzymes. Biochem. Biophys. Res. Comm. 34: 315–321.PubMedCrossRefGoogle Scholar
  14. Snyder, F., and Blank, M. L. 1969. Relationships of chain lengths and double bond locations in 0-alkyl, 0-alk-1-enyl, acyl, and fatty alcohol moieties in preputial glands of mice. Arch. Biochem. Biophys. 130: 101–110.PubMedCrossRefGoogle Scholar
  15. Spener, F., Mangold, H. K., Sansone, G., and Hamilton, J. G. 1969. Long-chain alkyl acetates in the preputial gland of the mouse. Biochim. Biophys. Acta 192: 516–521.PubMedCrossRefGoogle Scholar
  16. Stacewicz-Sapuntzakis, M., and Gawienowski, A. M. 1977. Rat olfactory response to aliphatic acetates, J. Chem. Ecol. (in press).Google Scholar
  17. Stanley, A. J., and Powell, R. A. 1941. Studies on the preputial gland of the white rat. Proc. Louisiana Acad. Sci. 5: 28–29.Google Scholar
  18. Steel, R. G. P., and Torrie, H. H. 1960. “Principles and Procedures of Statistics.” McGraw Hill, New York.Google Scholar
  19. Stevens, D. A., and Koster, E. P. 1972. Open-field responses of rats to odors from stressed and nonstressed predecessors. Behavioral Biol. 7: 519–525.CrossRefGoogle Scholar
  20. Valenta, J. G., and Rigby, M. K. 1968. Discrimination of the odor of stressed rats. Science 161: 599–601.PubMedCrossRefGoogle Scholar
  21. Whitten, W. K. 1966. Pheromones and Mammalian Reproduction. Advances in Reproductive Physiology, Vol. 1, pp. 155–177, A. McLaren (ed.). Academic Press, New York.Google Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Anthony M. Gawienowski
    • 1
  1. 1.Department of BiochemistryUniversity of MassachusettsAmherstUSA

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