Bacteria as a Source of Chemical Signals in Mammals

  • Eric S. Albone
  • Pauline E. Gosden
  • Georges C. Ware


Although it has long been known that microorganisms are, at least partially, responsible for odor, such as axillary odor (Shelley et al., 1953) and halitosis, or breath odor (Tonzetich et al., 1967, 1971), in man, only recently has it been suggested that microbially-derived odors might assume a chemical communicatory significance in mammals. This presents new opportunities for bacteriologists to contribute to multidisciplinary studies in mammalian chemical communication.


Volatile Fatty Acid Vulpes Vulpes Bacteriological Study Striped Skunk Axillary Odor 
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  1. ALBONE, E.S., EGLINTON, G., WALKER, J.M., and WARE, C.G. 1974. The anal sac secretion of the red fox, Vulpes vulpes; its chemistry and microbiology. A comparison with the anal sac secretion of the lion, Panthera leo. Life Sci. 14: 387–400.Google Scholar
  2. ALBONE, E.S., and GRONNEBERG, T.O. 1976. Lipids of the anal sac secretions of the red fox, Vulpes vulpes, and of the lion, Panthera leo. Submitted for publication.Google Scholar
  3. ALBONE, E.S., and PERRY, G.C. 1976. Anal sac secretion of the red fox, Vulpes vulpes; volatile fatty acids and diamines. Implications for a fermentation hypothesis of chemical recognition. J. Chem. Ecol. 2: 101–111.CrossRefGoogle Scholar
  4. ALBONE, E.S., ROBINS, S.P. and PATEL, D. 1976. 5-Aminovaleric acid, a major amino acid component of the anal sac secretion of the red fox, Vulpes vulpes. Comp. Biochem. Physiol., 55B: 483–486.Google Scholar
  5. ANDERSEN, K.K., and BERNSTEIN, D.T. 1975. Some chemical constituents of the scent of the striped skunk, Mephitis mephitis. J. Chem. Ecol., 1: 493–499.CrossRefGoogle Scholar
  6. ANEMA, P.J., KOOIMAN, W.T., and GEERS, J.M. 1973. Volatile acid production by Clostridium sporogenes under controlled conditions. J. Appl. Bact., 36: 683–687.Google Scholar
  7. BROOKS, J.B., and MOORE, W.E.C. 1969. Gas chromatographic analysis of amines and other compounds produced by several species of Clostridium. Can. J. Microbiol., 15: 1433–1447.Google Scholar
  8. DOELLE, H.W. 1975. Bacterial metabolism. Academic Press, New York and London.Google Scholar
  9. DRASAR, B.S., and HILL, M.J. 1974. Human intestinal flora, Academic Press, London and New York. 22–23.Google Scholar
  10. EGLINTON, G. (Ed.). 1975. Environmental Chemistry, Vol. 1, Specialist Periodical Report, The Chemical Society, London.Google Scholar
  11. EWER, R.F. 1973. The carnivores, Weidenfeld and Nicholson, London. 90–100.Google Scholar
  12. GODDARD, P., and HILL, M.J. 1974. The in vivo metabolism of cholesterol by gut bacteria in the rat and guineapig. J. Steroid Biochem., 5: 569–572.Google Scholar
  13. GORMAN, M.L., NEDWELL, D.B., and SMITH, R.M. 1974. An analysis of the anal scent pockets of Herpestes auropunctatus. J. Zool. 172: 389–399.Google Scholar
  14. GORMAN, M.L. 1976. A mechanism for individual recognition by odour in Herpestes auropunctatus. Anim. Behay. 24: 141–145.CrossRefGoogle Scholar
  15. GOSDEN, P.E., and WARE, G.C. 1976. The aerobic bacterial flora of the anal sac of the red fox. J. Appl. Bact. 41: 271–275.Google Scholar
  16. HERBERT, D. 1961. A theoretical analysis of continuous culture systems, in Continuous culture of microorganisms, Society of Chemical Industry, London, 21–53.Google Scholar
  17. HURLEY, R., STANLEY, V.C., LEASK, B.G.S. and DE LOUVOIS, J. 1974. Microflora of the vagina during pregnancy, in The normal microbial flora of man (F.A. Skinner and J.G. Carr, eds.) Academic Press, New York and London, 155–185.Google Scholar
  18. MARPLES, M.J. 1974. The normal microbial flora of the skin, in The normal microbial flora of man (F.A. Skinner and J.G. Carr, eds.) Academic Press, New York and London, 7–12.Google Scholar
  19. MICHAEL, R.P., ZUMPE, D., KEVERNE, E.B., and BONSALL, R.W. 1972. Neuroendocrine factors in the control of primate behavior. Recent Progr. Horm. Res., 28: 665–706.Google Scholar
  20. MICHAEL, R.P., BONSALL, R.W., and WARNER, P. 1975. Primate sexual pheromones, in Olfaction and Taste, Vol. 5, (D.A. Denton and J.P. Coghlan, eds.) Academic Press, New York and London, 417–424, 433–434.Google Scholar
  21. NOBLE, W.C., and SOMERVILLE, D.A. 1974. Microbiology of human skin, W.B. Saunders Co., London, Philadelphia, Toronto.Google Scholar
  22. PATTERSON, R.L.S. 1967. A possible contribution of phenolic components to boar odour. J. Sci. Fd. Ag., 18: 8–10.Google Scholar
  23. PATTERSON, R.L.S. 1968. Acidic components of boar preputial fluid. J. Sci. Fd. Ag., 19: 38–40.Google Scholar
  24. PRETI, G., and HUGGINS, G.R. 1975. Cyclical changes in volatile acidic metabolites of human vaginal secretions and their relation to ovulation. J. Chem. Ecol., 1: 361–376.Google Scholar
  25. PUHVEL, S.M., REISNER, R.M., and SAKAMOTO, M. 1975. Analysis of lipid composition of isolated human sebaceous gland homogenates after incubation with cutaneous bacteria. Thin layer chromatography. J. Invest. Derm., 64: 406–411.Google Scholar
  26. QUAY, W.B., and MÜLLER-SCHWARZE, D. 1970. Functional histology of integumentary glandular regions in black-tailed deer, Odocoileus hemionus columbianus. J. Mammal., 51: 675–694.Google Scholar
  27. SCHAFFER, J. 1940. Die Hautdrusenorgane der Saugetiere, Urban and Schwartzenberg, Berlin and Vienna.Google Scholar
  28. SHELLEY, W.B., HURLEY, H.J., and NICHOLS, A.C. 1953. Axillary odor. Arch. Derm. Syph., 68: 430–446.CrossRefGoogle Scholar
  29. SISSON, S. 1975. Sisson and Grossman’s The Anatomy of the Domestic Animals. (R. Getty, ed.) 5th edn., W.B. Saunders Co., London, Philadelphia and Toronto, p1210, 1301.Google Scholar
  30. TONZETICH, J., EIGEN, E., KING, W.J., and WEISS, S. 1967. Volatility as a factor in the ability of certain amines and indole to increase the odour of saliva. Archs. Oral Biol., 12: 1167–1175.Google Scholar
  31. TONZETICH, J., and CARPENTER, P.A.W. 1971. Production of volatile sulphur compounds from cysteine, cystine, and methionine by human dental plaque. Archs. Oral Biol., 16: 599–607.Google Scholar
  32. WOODROFFE, R.C.S., and SHAW, D.A. 1974. Natural control and ecology of microbial populations of skin and hair, in The normal microbial flora of man (F.A. Skinner and J.G. Carr, eds.) Academic Press, New York and London 13–34.Google Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Eric S. Albone
    • 1
  • Pauline E. Gosden
    • 2
  • Georges C. Ware
    • 2
  1. 1.Department of Animal HusbandryUniversity of BristolLandford, BristolUK
  2. 2.Department of BacteriologyUniversity of BristolBristolUK

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