Bilirubin Metabolism

  • Thomas R. C. Sisson


It was pointed out by With(122) in his exhaustive monograph on bile pigments that we are indebted to the work of Hans Fischer and his colleagues for much of our knowledge of the bile pigments. Their metabolism, principally that of bilirubin IXa, is of importance to the pediatrician because hyperbilirubinemia is singular among the common symptoms appearing in the newborn in that it in itself, regardless of cause, can produce severe and irrevocable damage to the developing CNS.


Serum Bilirubin Serum Bilirubin Level Bile Pigment Neonatal Jaundice Unconjugated Bilirubin 


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© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Thomas R. C. Sisson
    • 1
  1. 1.Department of Pediatrics, Obstetrics, and Gynecology (Perinatology), Neonatal Research LaboratoryTemple University School of MedicinePhiladelphiaUSA

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