Liver Enzymes

  • Uwe Stave


The metabolic activity of the liver is multifarious, and a discussion of perinatal changes in hepatic enzyme patterns embraces many areas of physiology and biochemistry. Most of the chapters in this Part III on metabolism and several chapters of the remaining parts of this volume deal with functions that proceed predominantly in the liver. Specific enzyme activities are discussed in connection with those different topics. In this chapter, an attempt will be made to present a survey of metabolic potentials in the perinatal liver, and to elucidate the developmental formation of hepatic enzymes. As much as it would be desirable to survey all liver enzymes, and preferably those of the human fetus and newborn, there are good ethical reasons for the restricted research on normal human tissues obtained in the perinatal period. The data that are available from human liver, however, demonstrate trends and principles very similar to those studied in subhuman mammals.


Perinatal Period Enzyme Protein Adult Level Rabbit Liver Phenylalanine Hydroxylase 


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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • Uwe Stave
    • 1
  1. 1.Mailman Center for Child Development and Department of PediatricsUniversity of Miami School of MedicineMiamiUSA

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