Blood as a Physicochemical System—I

Hemoglobin and Its Interaction with Ligands
  • Lars Garby
  • Jerry Meldon
Part of the Topics in Hematology book series (TOHE)


The analysis in the previous chapter placed the respiratory functions of the blood in relation to the total system of transport of oxygen and carbon dioxide and suggested those physicochemical properties of the blood that are the main determinants of its gas transport function. These properties include the equilibrium and kinetic characteristics of:
  1. 1.

    Oxygen and carbon dioxide binding to hemoglobin, and CO2 hydrolysis.

  2. 2.

    The distribution of carbon dioxide, oxygen, and protons between red cells and plasma.



Salt Bridge Oxygen Affinity Porphyrin Ring Oxygen Binding Hemoglobin Molecule 
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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • Lars Garby
    • 1
  • Jerry Meldon
    • 1
  1. 1.University of OdenseOdenseDenmark

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