The Radiology of Paget’s Disease

  • Alex Norman


Paget’s disease is characterized by active remodeling of bone; its radiologic characteristics follow the transformation of the gross and microscopic anatomy that occurs in both cortical and cancellous bone. Bone is ultimately remodeled into a coarse trabeculated pattern that when pieced together characterizes the mosaic architecture that distinguishes the condition1–3 (Figure 1.1). The disease progresses through three distinct phases of remodeling: the early osteolytic or “hot phase,” the intermediate or “mixed phase,” and ultimately the late sclerotic or “cooled-off phase.”


Giant Cell Tumor Pumice Stone Pagetic Bone Metastatic Bone Cancer Benign Giant Cell Tumor 
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© Elsevier Science Publishing Co., Inc. 1991

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  • Alex Norman

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