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Intercellular Communication and Cancer

  • Roobik Azarnia
  • William J. Larsen

Abstract

Among the several different forms of cell interactions known to exist in multicellular organisms intercellular communication provides the most direct form of communication by allowing free exchange of ions and small molecules between neighboring cells via permeable membrane junctions. This type of communication has been implicated in various biological functions such as cell differentiation, embryonic development, and tissue growth regulation. In this chapter we will review highlights of functional and structural evidence of junctional communication in normal and cancerous tissues and discuss the existing hypotheses concerning the possible significance of cell junctions in cancer.

Keywords

Granulosa Cell Intercellular Communication Septate Junction Ionic Coupling Membrane Junction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Roobik Azarnia
    • 1
  • William J. Larsen
    • 2
  1. 1.Department of Physiology and BiophysicsUniversity of Miami, School of MedicineMiamiUSA
  2. 2.Department of AnatomyThe University of Iowa, College of MedicineIowa CityUSA

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