Abstract
In 1945, Kety and Schmidt1 devised a method to measure cerebral blood flow using a diffusible indicator, nitrous oxide. In 1949, Kety2 substituted 24Na and described the first practical method to measure blood flow using a radionuclide tracer. In the following years, some groups3–11 elaborated further on Kety’s work and developed methods for measuring myocardial blood flow by injection of diffusible tracers into a coronary artery or into the myocardium itself. The disappearance, or “washout,” of radioactivity was measured by an external radiation-detection system placed over the myocardium. Kety had shown that the rate of washout of the diffusible indicator from tissue to blood was a function of tissue blood flow.1,2,12
Keywords
- Myocardial Blood Flow
- Regional Myocardial Blood Flow
- Experimental Myocardial Infarction
- Transmural Infarction
- Regional Myocardial Perfusion
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References
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Parkey, R.W., Bonte, F.J., Stokely, E.M., Curry, G.C., Willerson, J.T. (1977). Measurement of Myocardial Blood Flow Using 133Xe. In: Serafini, A.N., Gilson, A.J., Smoak, W.M. (eds) Nuclear Cardiology. Topics in Cardiovascular Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2274-0_9
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