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Electrophysiological Properties of the Uterine Smooth Muscle

  • Chapter
Biology of the Uterus

Abstract

Until recently, almost all knowledge of the electrophysiological properties of the myometrium was based on descriptive observations of some natural phenomena, or modifications of such phenomena by changes in the ionic environment or by hormonal and pharmacological agents. Although much has been learned about the resting potential and the action potential, the information derived from such approaches has to be limited because of the nature of the methods. Since the first edition of this book, other methods have been developed or successfully adapted for use on mammalian smooth muscles that permit a deeper analytical probing of some fundamental electrophysiological properties of smooth muscles. The newer methods include application of massive extrapolar currents for analysis of passive electrical properties of smooth muscles (Abe and Tomita, 1968) and use of a double sucrose–gap method for current–clamp and voltage–clamp studies (Anderson, 1969). Serious technical difficulties still persist in studying smooth muscles in general, and, in some areas, are compounded by the application of these newer methods. Nevertheless, the progress in recent years has been substantial and encouraging.

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Authors and Affiliations

  1. Department of Pharmacology, State University of New York, Downstate Medical Center, Brooklyn, New York, USA

    C. Y. Kao

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  1. C. Y. Kao
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  1. University of Illinois at the Medical Center, Chicago, Illinois, USA

    Ralph M. Wynn

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© 1977 Plenum Press, New York

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Kao, C.Y. (1977). Electrophysiological Properties of the Uterine Smooth Muscle. In: Wynn, R.M. (eds) Biology of the Uterus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2271-9_13

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  • DOI: https://doi.org/10.1007/978-1-4684-2271-9_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2273-3

  • Online ISBN: 978-1-4684-2271-9

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