Interaction of Low Density Lipoproteins with Small and Large Molecules

  • Santibrata Ghosh


The metabolic fate and the biological functions of a molecule depend primarily on the interactions it may undergo in the physiological milieu. The plasma concentration of LDL, for example, will depend on its interactions with lipolytic and other enzymes as well as with certain cells. In the plasma compartment, LDL may have a role in carrying certain metal ions, free fatty acids, drugs, and other substances. Within arterial tissue, interaction with connective tissue components may be the initial reaction in atherogenesis. Studies on the interaction of LDL with agents as mentioned above are thus directly relevant to the understanding of the biological role of LDL.


Free Fatty Acid Ionic Strength Hyaluronic Acid Electrophoretic Mobility Titration Curve 


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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Santibrata Ghosh
    • 1
  1. 1.Department of Biochemistry, Medical and Dental SchoolsNorthwestern UniversityChicagoUSA

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