The Lateral Olfactory Tract, the Anterior Commissure, and Other Olfactory Connections

  • Leonard W. Hamilton


Although all complex organisms utilize multisensory input to monitor the external environment, each species appears to have one system which is predominantly used. For man and most avian species, the dominant sensory system is vision. For rats and many other species of rodents, the dominant sensory system is olfaction. It is necessary to consider the olfactory system in some detail not only because it represents the primary source of sensory input for the rat, but also because of its close interrelationship with the structures of the limbic system; the notion that the primary function of the limbic system (rhinencephalon) was to process olfactory information is also of historical importance (cf. Chapter 1 and Brodai, 1947).


Olfactory Bulb Limbic System Olfactory System Anterior Commissure Mitral Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Allison, A.C. The structure of the olfactory bulb and its relations to the olfactory pathways in the rabbit and the cat. J. Comp. Neurol., 98: 309–353, 1953.PubMedCrossRefGoogle Scholar
  2. Brodal, A. The hippocampus and the sense of smell. Brain, 70: 179–222, 1947.PubMedCrossRefGoogle Scholar
  3. Brodal, A. The origin of fibers of the anterior commissure in the rat. Experimental studies. J. Comp. Neurol., 88: 157–205, 1948.PubMedCrossRefGoogle Scholar
  4. DeVries, H., and Stuiver, M. The absolute sensitivity of the human sense of smell. In Rosenblith, W.A. (Ed.): Sensory Communication, New York, Wiley, 1959, pp. 159–167.Google Scholar
  5. Druga, R. Projection area of the olfactory bulb in the rat. Folio Morphol. (Praha), 21: 328–329, 1973.Google Scholar
  6. Druga, R. The projection field of the prepyriform cortex (an experimental study using Nauta’s method). Folio Morphol. (Praha), 20: 169–171, 1972.Google Scholar
  7. Ferrer, N.G. Efferent projections of the anterior olfactory nucleus. J. Comp. Neurol., 137: 309–320, 1969.PubMedCrossRefGoogle Scholar
  8. Gurdjian, E.S. Olfactory connections in the albino rat, with special reference to the stria medullaris and the anterior commissure. J. Comp. Neurol., 38: 127–163, 1925.CrossRefGoogle Scholar
  9. Heimer, L. The olfactory connections of the diencephalon in the rat. An experimental light-and electron-microscopic study with special emphasis on the problem of terminal degeneration. Brain Behay. Evol., 6: 484–523, 1972.CrossRefGoogle Scholar
  10. Land, J.L., Eager, R.P., and Shepherd, G.M. Olfactory nerve projections to the olfactory bulb in rabbit: demonstration by means of a simplified ammoniacal siver degeneration method. Brain Res., 23: 250–254, 1970.PubMedCrossRefGoogle Scholar
  11. Lohman, A.H., and Mentink, G.M. The lateral olfactory tract, the anterior commissure and the cells of the olfactory bulb. Brain Res., 12: 396–413, 1969.PubMedCrossRefGoogle Scholar
  12. Milner, P.M. Physiological Psychology. New York, Holt, Rinehart and Winston, 1970.Google Scholar
  13. Minckler, J. Introduction to Neuroscience. St. Louis, Mosby, 1972.Google Scholar
  14. Nicoll, R.A. Recurrent excitatory pathways of anterior commissure and mitral cell axons in the olfactory bulb. Brain Res., 19: 491–493, 1970.PubMedCrossRefGoogle Scholar
  15. Powell, T.P.S., Cowan, W.M., and Raisman, G. The central olfactory connexions. J. Anat., 99: 791–813, 1965.PubMedGoogle Scholar
  16. Price, J.L. The origin of the centrifugal fibers to the olfactory bulb. Brain Res., 14: 542–545, 1969.PubMedCrossRefGoogle Scholar
  17. Price, J.L., and Powell, T.P. An electron-microscopic study of the termination of the afferent fibres to the olfactory bulb from the cerebral hemisphere. J. Cell Sci., 7: 157–187, 1970.PubMedGoogle Scholar
  18. Price, J.L., and Powell, T.P. An experimental study of the origin and course of the centrifugal fibres to the olfactory bulb in the rat. J. Anat. 707: 215–237, 1970.Google Scholar
  19. Price, J.L., and Powell, T.P. The afferent connexions of the nucleus of the horizontal limb of the diagonal band. J. Anat., 107: 239–256, 1970.PubMedGoogle Scholar
  20. Price, J.L., and Sprich, W.W. Observations on the lateral olfactory tract of the rat. J. Comp. Neurol., 162: 321–336, 1975.PubMedCrossRefGoogle Scholar
  21. Raisman, G. An experimental study of the projection of the amygdala to the accessory olfactory bulb and its relationship to the concept of a dual olfactory system. Exp. Brain Res., 14: 395–408, 1972.PubMedCrossRefGoogle Scholar
  22. Scalia, F., and Winans, S.S. The differential projections of the olfactory bulb and accessory olfactory bulb in mammals. J. Comp. Neurol., 761: 31–55, 1975.CrossRefGoogle Scholar
  23. Scott, J.W., and Chafin, B.R. Origin of olfactory projections to lateral hypothalamus and nuclei gemini of the rat. Brain Res., 88: 64–68, 1975.PubMedCrossRefGoogle Scholar
  24. Shepherd, G.M. Synaptic organization of the mammalian olfactory bulb. Physiol. Rev., 52: 864–917, 1972.PubMedGoogle Scholar
  25. Sinclair, J.G. Reflections on the role of receptor systems for taste and smell. Int. Rev. Neurobiol., 14: 159–171, 1971.PubMedCrossRefGoogle Scholar
  26. Leonard, C.W., and Scott, J.W. Origin and distribution of the amygdalofugal pathways in the rat: an experimental study. J. Comp. Neurol., 141: 313–330, 1971.PubMedCrossRefGoogle Scholar
  27. Loo, Y.T. The forebrain of the opossum, Didelphius virginiana, Part I. Gross anatomy. J. Comp. Neurol., 51: 13–64, 1930.CrossRefGoogle Scholar
  28. Thamke, B., Schulz, E. and Schönheit, B. Neurohistological studies on the olfactory bulb of the adult white laboratory rat (Rattus norvegicus, forma alba). J. Hirnforsch., 14: 435–449, 1973.PubMedGoogle Scholar
  29. Tucker, G.F., Jr., Alonso, W.A., Cowan, M., Tucker, J.A., and Druck, N. The anterior commissure revisited. Ann. Otol. Rhinol. Laryngol., 82: 625–636, 1973.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Leonard W. Hamilton
    • 1
  1. 1.Rutgers UniversityNew BrunswickUSA

Personalised recommendations