Membranes as a Tool for the Study of Cell Surface Recognition

  • R. Merrell
  • D. I. Gottlieb
  • L. Glaser
Part of the Current Topics in Neurobiology book series (CTNB)


It has been known for many years, since the early work of Townes and Holtfreter (1955) and Moscona and Moscona (1952), that embryonal tissues can be dissociated into single cells and that aggregates obtained by centrifuging single cells from different tissues into a pellet will ultimately segregate in culture so that homologous cells are in contact with one another. This phenomenon could be due to specific cell adhesion, chemotaxis, or a combination of these effects (Steinberg, 1963; Moscona, 1965).


Nerve Growth Factor Cell Aggregation Retinal Cell Optic Tectum Neural Retina 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • R. Merrell
    • 1
  • D. I. Gottlieb
    • 1
  • L. Glaser
    • 1
  1. 1.Department of Biological Chemistry, Division of Biology and Biomedical SciencesWashington University School of MedicineSt. LouisUSA

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