Membranes as a Tool for the Study of Cell Surface Recognition
It has been known for many years, since the early work of Townes and Holtfreter (1955) and Moscona and Moscona (1952), that embryonal tissues can be dissociated into single cells and that aggregates obtained by centrifuging single cells from different tissues into a pellet will ultimately segregate in culture so that homologous cells are in contact with one another. This phenomenon could be due to specific cell adhesion, chemotaxis, or a combination of these effects (Steinberg, 1963; Moscona, 1965).
KeywordsNerve Growth Factor Cell Aggregation Retinal Cell Optic Tectum Neural Retina
Unable to display preview. Download preview PDF.
- Barbera, A. J., Marchase, R. B., and Roth, S., 1973, Adhesive recognition and retinotectal specificity, Proc. Natl. Acad. Sci. USA 70: 2482.Google Scholar
- Frazier, W. A., Ohlendorf, C. E., Boyd, L. F., Aloe, L., Johnson, E. M., Ferendelli, J. A., and Bradshaw, R. A., 1973a, Mechanism of action of nerve growth factor and cyclic AMP on neurite outgrowth of embryonic chick sensory ganglia: Demonstration of independent pathway of stimulation, Proc. Natl. Acad. Sci. USA 70: 2448.CrossRefGoogle Scholar
- Frazier, W. A., Boyd, L. F., and Bradshaw, R. A., 1974, Properties of the specific binding of ‘25I-nerve growth factor to responsive peripheral neurons, J. Biol. Chem. 249: 5513.Google Scholar
- Jones, R. E., Moscona, M. H., and Moscona, A. A., 1974, Induction of glutamine synthetase in cultures of embryonic neural retina, J. Biol. Chem. 249: 6021.Google Scholar
- Levi-Montalcini, R., Aloe, L., and Johnson, E. M., 1973, Interaction between nerve growth factor and adrenergic blocking agents in sympathetic neurons, in: Biochemical Pharmacology Supplement I ( E. Usdin and S. H. Snyder eds.), pp. 199–208, Pergamon Press, New York.Google Scholar
- Moore, S., and Stein, W., 1948, Photometric ninhydrin method for use in the chromatography of amino acids, J. Biol. Chem. 179: 367.Google Scholar
- Moscona, A. A., 1965, Recombination of dissociated cells and the development of cell aggregates, in: Cells and Tissues in Culture ( E. N. Willmer, ed.), pp. 489–529, Academic Press, New York.Google Scholar
- Moscona, A., and Moscona, H., 1952, The dissociation and aggregation of cells from organ rudiments of the early chick embryo, J. Anal. 86: 287.Google Scholar
- Orr, C. W., and Roseman, S., 1969, Intercellular adhesion: A quantitative assay for measuring the rate of adhesion, J. Membr. Biol. 1: 110.Google Scholar
- Schwartz, R. J., 1973, Control of glutamine synthetase synthesis in the embryonic chick neural retina, J. Biol. Chem. 248: 6426.Google Scholar
- Warburg, O., and Christian, W., 1941, Isolierung and Kristallisation des Garungsferments Enolase, Biochem. Z. 310: 384.Google Scholar