Models of Distributed Passive Membrane
In Chapters 3, 4, and 5, we have presented models of local membrane phenomena. In other words, we have dealt with gradients and ion flows across the membrane, but we have ignored gradients and flows directed tangential to its surfaces, and in doing so we have ignored mechanisms by which receptor responses and synaptic responses can spread from one region of the neuron to another. As we mentioned in Chapters 1 and 2, local regions of a neuron are often apparently adapted to specific subtasks with respect to signal processing. Quite often, for example, sites of sensitivity to external stimuli (receptor sites) are separated spatially (and are often quite remote) from spike-triggering sites. The influencing of spike generation by receptor-site responses is generally accepted as being a key link in the neuron’s signal processing; and, of course, the spread of the receptor response from the receptor site to the triggering site is the crucial phenomenon in this link.
KeywordsBranch Point Receptor Site Neural Modeling Membrane Conductance Dendritic Tree
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