Oxytocin Effect on the Depolarized Rat Uterus: A Mathematical Approach Using System Identification
It is becoming increasingly recognized that “classical” pharmacological receptor theory, operating with relatively few fundamental concept such as receptor binding, stimulus generation, and stimulus-effect coupling is not fully adequate in describing the behaviour of actual experimental systems /1/. Nor have the recent advances in molecular endocrinology, however important in themselves, contributed to this particular problem since they have mainly been concerned with simplified biological systems at the cellular or subcellular level.
KeywordsTransfer Function Hormone Concentration Organ Bath Receptor Compartment Parallel Branch
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