Maturation Dependence of Adenylate Cyclase in Red Blood Cells
Originally adenylate cyclase activity was found only in nucleated erythrocytes (1). Sheppard and Burghardt demonstrated its occurrence and its stimulation by catecholamines and NaF also in the cell membrane of mammalian erythrocytes (2). Gauger et.al. (3) concluded, that adenylate cyclase was confined mainly to the reticulocytes.
KeywordsAdenylate Cyclase Density Gradient Centrifugation Adenylate Cyclase Activity Brilliant Cresyl Blue Inorganic Pyrophosphatase
Unable to display preview. Download preview PDF.
- 6.Rapoport, S.M., Rosenthal, S., Schewe, T., Schultze, M. and Müller, M. in: Cellular and Molecular Biology of Erythrocytes ed. by H.Yoshikawa and S.M. Rapoport, Univ. Tokyo Press, Tokyo, pp. 93–141 (1974)Google Scholar
- 8.Krishna, G. and Weiss, B.: Pharmac. Exp. Ther. 163, 379–385 (1968)Google Scholar
- 10.Schooley, J.C. and Mahlmann, L.J.: Proc. Soc. Exp. Biol. Med. 137, 1289–1292 (1971)Google Scholar
- 11.Nörris, A., Gorshein, D., Besa, E.C., Leonard, R. A. and Gardener, F. H.: Proc. Soc. Exp. Biol. Med. 145, 975–78 (1974)Google Scholar