Diverticular Disease (Pathology)
Perhaps Professor Arthur Keith, who described the pathology of diverticula of the alimentary tract in an article in the British Medical Journal in 1910, should be the person to deliver this paper (Keith, 1910). If alive today he would be 110 years old and hence a little elderly for flying the Atlantic! In that paper he described colonic diverticula as true invaginations of the epithelium through the bowel wall, caused probably by increased luminal pressure. He noted that the taeniae were contracted and the circular muscle was thrown into folds, like a concertina. He also observed that diverticula occurred at points of weakness in the colonic wall where it was penetrated by blood vessels. Since that publication, surgical pathologists have been able to improve but little on the description of the pathological changes in diverticular disease.
KeywordsSigmoid Colon Diverticular Disease Circular Muscle Fiber Intake Colonic Wall
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- Arfwidsson, S., 1964, Pathogenesis of multiple diverticula of the sigmoid colon in diverticular disease, Acta Chir. Scand. ( Suppl ), 342.Google Scholar
- Keith, A., 1910, Diverticula of the alimentary tract of congenital or obscure origin, Brit. Med. J., p. 376.Google Scholar
- Manousos, O. N. and Vrachliotis, G., etal., 1973, Relation of diverticulosis of the colon to environmental factors in Greece, Am. J. Dig. Dis., 18: 174–176.Google Scholar