Biogenetic Autonomy of Mitochondria and Its Limits

Some Questions and New Approaches to Their Answer
  • Henry R. Mahler
  • Roberto N. Bastos
  • Fred Feldman
  • Urs Flury
  • Chi Chung Lin
  • Philip S. Perlman
  • Sem H. Phan


The past ten years have seen such an almost explosive growth of efforts devoted to studies on mitochondrial biogenesis that they occupy at least as much contemporary journal space as do studies on mitochondrial function and energetics, their much more venerable companions. The results of this endeavor have been fairly spectacular: the documentation of the existence and the characteristics, in molecular terms, of a novel and separate system for the maintenance, duplication, and expression of genetic information within the organelle and its interaction with the classical nucleocytosolic system of the eukaryotic cell (for recent reviews see refs. 1–10).


Cytochrome Oxidase None None Catabolite Repression Mitochondrial Mass Beef Heart 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Henry R. Mahler
    • 1
  • Roberto N. Bastos
    • 1
  • Fred Feldman
    • 1
  • Urs Flury
    • 1
  • Chi Chung Lin
    • 1
  • Philip S. Perlman
    • 2
  • Sem H. Phan
    • 1
  1. 1.Mitochondrial Biogenesis Group, Chemical LaboratoriesIndiana UniversityBloomingtonUSA
  2. 2.Department of GeneticsOhio State UniversityColumbusUSA

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