Advertisement

Intergenic Recombination, DNA Replication and Synaptonemal Complex Formation in the Drosophila Oocyte

  • Rhoda F. Grell
  • J. W. Day

Abstract

The transition from microbial systems to the higher eukaryotes introduces a different order of time and physical dimensions. For recombination studies the change confers both advantages and disadvantages. The increased complexity of the organism imposes difficulties in isolating meiocytes free of somatic cells and other germ cells for the kinds of molecular approaches that have been used so successfully in prokaryotes, but the increased complexity also entails a temporal extension and compartmentalization of meiotic events which, for some studies, simplifies their dissection and examination.

Keywords

Synaptonemal Complex Nurse Cell Oocyte Nucleus SYNAPTONEMAL Complex Formation Positive Interference 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Abel, W. O. 1965. Über den Beitpunkt des Crossing-Over und der Chromosomenverdopplung bei Sphaerocarpus. Z. Vererbungsl. 96: 228.PubMedCrossRefGoogle Scholar
  2. Abel, W. O. 1968. Time of crossing-over in Sphaerocarpos. Proc. 12th Int. Congr. Genet. 1: 70.Google Scholar
  3. Callan, H. G. 1973. DNA replication in the chromosomes of eukaryotes. In (B. A. Hamkalo and J. Papaconstantinou, ed.) Molecular Cytogenetics, p. 31. Plenum Press, New York-London.Google Scholar
  4. Day, J. W. 1974. Temporal relationship between premeiotic DNA synthesis and heat-induced recombination in oocytes of Drosophila melanogaster. In preparation.Google Scholar
  5. Gillies, C. B. 1973. Ultrastructural analysis of maize pachytene karyotypes by three dimensional reconstruction of the synaptonemal complexes. Chromosoma 43: 145.CrossRefGoogle Scholar
  6. Grell, R. F. 1967. Pairing at the chromosomal level. J. Cell. Physiol. 70. (Suppl. 1): 119.PubMedCrossRefGoogle Scholar
  7. Grell, R. F. 1969. Meiotic and somatic pairing. In (E. W. Caspari and A. W. Ravin, eds.) Genetic Organization, vol. 1, p. 361. Academic Press, New York.Google Scholar
  8. Grell, R. F. 1971a. Induction of sex chromosome non-disjunction by elevated temperature. Mutation Res. 11: 347.Google Scholar
  9. Grell, R. F. 1971b. Heat-induced exchange in the fourth chromosome of diploid females of Drosophila melanogaster. Genetics 69: 523.Google Scholar
  10. Grell, R. F. 1973. Recombination and DNA replication in the Drosophila melanogaster oocyte. Genetics 73: 87.PubMedGoogle Scholar
  11. Grell, R. F. and A. C. Chandley. 1965. Evidence bearing on the coincidence of exchange and DNA replication in the oocyte of Drosophila melanogaster. Proc. Nat. Acad. Sci. U.S.A. 53: 1340.CrossRefGoogle Scholar
  12. Henderson, S. A. 1966. Time of chiasma formation in relation to the time of deoxyribonucleic acid synthesis. Nature 211: 1043.PubMedCrossRefGoogle Scholar
  13. King, R. C, A. C. Rubinson and R. F. Smith. 1956. Oogenesis in adult Drosophila melanogaster. Growth 20: 121.PubMedGoogle Scholar
  14. Lu, B. C. 1969. Genetic recombination in Coprinus. I: Its precise timing as revealed by temperature treatment experiments. Can. J. Genet. Cytol. 11: 434.Google Scholar
  15. Maguire, M. P. 1968. Evidence on the stage of heat induced crossover effect in maize. Genetics 60: 353.PubMedGoogle Scholar
  16. Moens, P. B. and F. O. Perkins. 1969. Chromosome number of a small protist: Accurate determination. Science 166: 1289.PubMedCrossRefGoogle Scholar
  17. Muller, H. J. 1916. The mechanism of crossing-over. I-IV. Amer. Nat. 50: 284, 350, 421.CrossRefGoogle Scholar
  18. Peacock, W. J. 1970. Replication, recombination and chiasmata in Goniaea australasiae (Orthoptera:Acrididae). Genetics 65: 593.PubMedGoogle Scholar
  19. Pritchard, R. H. 1955. The linear arrangement of a series of alleles in Aspergillus nedulans. Heredity 9: 343.CrossRefGoogle Scholar
  20. Wettstein, R. and J. R. Sotelo. 1967. Electron microscope serial reconstruction of the spermatocyte I nuclei at pachytene. J. Microscopie 6: 557.Google Scholar

Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Rhoda F. Grell
    • 1
  • J. W. Day
    • 1
  1. 1.Biology DivisionOak Ridge National LaboratoryOak RidgeUSA

Personalised recommendations