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The Isolation of Mitotic rec- Mutants in Schizosaccharomyces pombe

  • Stephen L. Goldman
  • Herbert Gutz

Abstract

The mechanisms governing the interaction of homologous DNA molecules that lead to the formation of genetic recombinants remain largely unknown in eukaryotes. Recent evidence (for review see Stern and Hotta, 1973) obtained from work with several species of Lilium indicates that the enzymatic control of recombination may be similar to that observed in bacteria and viruses. Given the fact that a portion of the genome directs the synthesis of enzymes that mediate recombination, additional information relating to its biochemistry could be obtained by selecting for mutants that alter genetic map distances. Presumably such an altered phenotype, e.g. absence of genetic recombination, would arise as a consequence of a modified or missing gene product that mediates exchange.

Keywords

Mating Type Schizosaccharomyces Pombe Intragenic Recombination Minimal Agar Ade6 Locus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Stephen L. Goldman
    • 1
  • Herbert Gutz
    • 2
  1. 1.Department of BiologyThe University of ToledoToledoUSA
  2. 2.Division of Biological SciencesThe University of Texas at DallasDallasUSA

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