Transduction of recB- Hosts is Promoted by λ red+ Function
The redB and redX genes of bacteriophage λ specify a recombination pathway that efficiently recombines phage genomes in lytically infected recA- and recB- cells (see Signer, 1971, for a review). However, the red genes do not promote efficient specialized transduction of a recA- host (Manly et al., 1969; Mizuuchi and Fukasawa, 1969; Gottesman et al., 1974; H. Echols, personal communication). We report here that the red pathway does promote efficient transduction of redB- hosts.
KeywordsCold Spring Harbor Laboratory Cell Ratio Infected recA Phage Recombination Transduce Phage
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