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Exchange of Parental DNA during Genetic Recombination in Bacteriophage φX174

  • Robert M. Benbow
  • Anthony J. Zuccarelli
  • Alma J. Shafer
  • Robert L. Sinsheimer

Summary

Two-factor crosses were performed between am mutants of φX174 in which one or both of the single-stranded parental bacteriophages were labeled with heavy isotopes. Recombinants were formed that contained DNA from each of the two parental phages and were composed almost entirely of parental RF DNA. A small amount of the parental-strand DNA (less than 700 nucleotides on the average) was removed and replaced during the formation of a recombinant molecule.

Keywords

Heavy Isotope Genetic Recombination Recombinant Formation Strand Bias Recombinant Molecule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Robert M. Benbow
    • 1
  • Anthony J. Zuccarelli
    • 1
  • Alma J. Shafer
    • 1
  • Robert L. Sinsheimer
    • 1
  1. 1.Division of BiologyCalifornia Institute of TechnologyPasadenaUSA

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