Abstract
Moses et al. (1970) have found an absolute ATP requirement, besides the four dNTP, for DNA replication in a toluene treated po1A −1 mutant. None of the known E. coli DNA polymerases are affected by ATP (Kornberg et al. 1970). Two major hypotheses can be considered to explain the role of ATP: ATP is a cofactor for some enzyme necessary to replication and/or it is a precursor for RNA synthesis involved in the priming of Okazaki pieces (Sugino et al. 1972).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Bibliography
Cousin, O. et Buttin, G. (1969) Annales de l’Institut Pasteur, Tome 117.
Gefter, M. L., Hirota, Y., Kornberg, T., Wechsler, J. A. and Barnoux, C. (1971) Proc. Nat. Acad. Sci. (USA) 68, 3150–53.
Gross, J. (1972) Current Topics in Microbiology and Immunology, 57.
Kohiyama, M. and Kolber, A. (1970) Nature, 228, 1157.
Romberg, T. and Gefter, M. L. (1970) Biochem. Biophys. Res. Commun. 40, 1348–55.
Moses, R. E. and Richardson, C. C. (1970) Proc. Nat. Acad. Sci. (USA) 67, 674–81.
Pizetsky, D., Berkower, I., Wickner, R. and Hurwitz, J. (1972) J. Mol. Biol. 71, 557–572.
Schekman, R., Wickner, W., Westergaard, O., Brutlag, D., Geider, K., Bertsch, L. and Kornberg, A. (1972) Proc. Nat. Acad. Sci. (USA) 69, 2691–95.
Sekiguchi, M. and Lida, S. (1967) Proc. Nat. Acad. Sci, (USA) 58, 2315–20.
Smith (1971) Cold Spring Harbour DNA Meeting.
Sugino, A., Hirose, S. and Okazaki, R. (1972) Proc. Nat. Acad. Sci. (USA) 69, 1863–67.
Sugino, A., Okazaki, R. (1973) Proc. Nat. Acad. Sci. (USA) 70, 88–92.
Milewski, E. and Kohiyama, M. (1973) J. Mol. Biol. 78, 229–235.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1974 Plenum Press, New York
About this chapter
Cite this chapter
Forterre, P., Kohiyama, M. (1974). The Role of ATP in Chromosome Replication Studied in Toluenized Escherichia coli . In: Kolber, A.R., Kohiyama, M. (eds) Mechanism and Regulation of DNA Replication. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2124-8_4
Download citation
DOI: https://doi.org/10.1007/978-1-4684-2124-8_4
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-2126-2
Online ISBN: 978-1-4684-2124-8
eBook Packages: Springer Book Archive