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Initiation of DNA Synthesis

  • Arthur Kornberg

Abstract

All the polymerases studied have two basic features: (i) a phosphodiester bridge is formed between the 3’-phosphate group of a deoxyribonucleotide and the 5’-hydroxy1 group at the growing end of a DNA chain called primer DNA; the chain growth is 5’→ 3’; and (ii) each deoxynucleotide added to the chain is selected by base-pair matching to a DNA chain called template DNA.

Keywords

Soluble Extract Replicative Form Chromosome Replication Phospho Cellulose Ribonucleoside Triphosphate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Arthur Kornberg
    • 1
  1. 1.Department of BiochemistryStanford University Medical SchoolStanfordUSA

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