Overlapping Pathways for Replication, Recombination and Repair in Bacteriophage Lambda
Work in our laboratory over the last few years has centered on the molecular events which occur during intracellular DNA replication of bacteriophage lambda. We have approached the problem in two ways: one series of experiments has involved analysis of replicative intermediates formed at various times after normal phage infection. A second series involved study of presumed intermediates that accumulate after the introduction of mutational blocks. Our results, together with those of others (see Kaiser, 1971, for review) have suggested that replication of lambda DNA occurs in two distinct stages.
KeywordsGeneral Recombination Bacteriophage Lambda Late Replication Circular Molecule Recombination Function
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