DNA-Unwinding Proteins and their Role in the Replication of DNA

  • Bruce Alberts


The first “DNA-unwinding protein” to be characterized was the T4 bacteriophage gene 32-protein (Alberts and Frey, 1970). Since then, other proteins of similar type have been obtained from a variety of organisms. In this article, I would like to review some of their properties and discuss their possible roles in DNA replication.


Replication Fork Template Strand Replication Apparatus Extended Linear Complex 
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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Bruce Alberts
    • 1
  1. 1.Department of Biochemical SciencesPrinceton UniversityUSA

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