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Peptides and Amino Acids in the Primordial Hydrosphere

  • Klaus Dose

Abstract

In this paper Oparin’s original concept of the primordial ocean being a “primeval broth” in which “protobionts” have evolved is reviewed on the basis of recent and previous data on the formation and decomposition of peptides and amino acids. It will be shown that peptides and amino acids could never reach significant concentrations in the ocean. Locally, in pools of transient existence, however, amino acids, peptides, and other molecules of biological significance could have been concentrated by various geological processes to yield a “primeval broth” in which prebiotic systems such as proteinoid microspheres and coacervate droplets, could have evolved.

Keywords

Free Amino Acid Amino Acid Production Volcanic Emission Peptide Bond Hydrolysis Simple Peptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Borsook, H., and Huffman, H. M., in: “Chemistry of the Amino Acids and Proteins” ( Schmidt, C.L.A., ed.), p. 822, Charles C Thomas, Springfield, Ill., 1944.Google Scholar
  2. 2.
    Borsook, H., Advances Protein Chem. 8, 127 (1953).PubMedCrossRefGoogle Scholar
  3. 3.
    Borsook, H., Chemical Pathways of Metabolism 2, 173 (1954).Google Scholar
  4. 4.
    Dixon, M. A., and Webb, E. C., “Enzymes,” p. 666, Academic Press, New York, 1958.Google Scholar
  5. 5.
    Fruton, J. S., and Simmonds, S., “General Biochemistry,” p. 712, 2nd ed., Wiley, New York, 1958.Google Scholar
  6. 6.
    Fox, S. W., and Dose, K., “Molecular Evolution and the Origin of Life,” Freeman, San Francisco, 1972.Google Scholar
  7. 7.
    Jager, C. de, in: “Radiation Research” ( Silini, G., ed.), North-Holland, Amsterdam, 1967.Google Scholar
  8. 8.
    Hull, D. E., Nature 186, 693 (1960).CrossRefGoogle Scholar
  9. 9.
    Abelson, P. H., Mem. Geol. Soc. Amer. II 67, 87 (1957).Google Scholar
  10. 10.
    Conway, D., and Libby, W. F., J. Am. Chem. Soc. 80, 1077 (1958).CrossRefGoogle Scholar
  11. 11.
    Vallentyne, J. R., Carnegie Inst. Wash. Yearbook 56, 185 (1956).Google Scholar
  12. 12.
    McLaren, A. D., and Shugar, D., “Photochemistry of Proteins and Nucleic Acids,” p. 97, Pergamon Press, Oxford, 1964.Google Scholar
  13. 13.
    Berkner, L. V., and Marshall, L. C., J. Atmos. Sci. 22, 225 (1965).CrossRefGoogle Scholar
  14. 14.
    Berkner, L. V., and Marshall, L. C., J. Atmos. Sci. 23, 133 (1966).CrossRefGoogle Scholar
  15. 15.
    Pocklington, R., Nature 230, 374 (1971).CrossRefGoogle Scholar
  16. 16.
    Abelson, P. H., in: “Organic Geochemistry” ( Breger, I. A., ed.), Pergamon, Oxford, 1963.Google Scholar
  17. 17.
    Rubey, W. W., Geol. Soc. Amer. Bull. 62, 111 (1951).CrossRefGoogle Scholar
  18. 18.
    Rubey, W. W., Geol. Soc. Amer. Spec. Paper 62, 631 (1955).Google Scholar
  19. 19.
    Urey, H. C., “The Planets,” Yale University Press, New Haven, 1952.Google Scholar
  20. 20.
    Bernal, J. D., “The Physical Basis of Life,” Routledge and Kegan Paul, London, 1951.Google Scholar
  21. 21.
    Bernal, J. D., in: “Proceedings of the First Intern. Symp. on Origin of Life on the Earth,” Moscow, 1957; pp. 23–35, Pergamon, London, 1959.Google Scholar
  22. 22.
    Fox, S. W., Vegotsky, A., Harada, K., and Hoagland, P. D., Ann. N.Y. Acad. Sci. 69, 328 (1957).PubMedCrossRefGoogle Scholar
  23. 23.
    Florkin, M., in: “Chemical Evolution and the Origin of Life,” Molecular Evolution, Vol. 1 (Buvet, R., and Ponnamperuma, C., eds.), p. 10, North-Holland, Amsterdam, 1971.Google Scholar
  24. 24.
    Hare, P. E., in: “Organic Geochemistry,” Results and Methods, p. 438, Springer Verlag, New York, 1969.Google Scholar
  25. 25.
    Fox, S. W., Science 132, 200 (1960).PubMedCrossRefGoogle Scholar
  26. 26.
    Jong, H.G.B, de, Dekker, W.A.L., and Gwan, O. S., Biochem. Z. 221, 392 (1930).Google Scholar
  27. 27.
    Oparin, A. I., in: “The Origins of Prebiological Systems” ( Fox, S. W., ed.), p. 331, Academic Press, New York, 1965.Google Scholar
  28. 28.
    Oparin, A. I., “The Origin and Initial Development of Life,” Meditsina Publishing House, Moscow, 1966.Google Scholar
  29. 29.
    Evreinova, T., and Bailey, A., Dokl. Akad. Nauk SSR 179, 723 (1968).Google Scholar
  30. 30.
    Donn, B., Science 170, 1116 (1970).PubMedCrossRefGoogle Scholar
  31. 31.
    Fox, S. W., and Windsor, C. R., Science 170, 984 (1970).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Klaus Dose
    • 1
  1. 1.Institut für BiochemieUniversität MainzMainzDeutschland

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