The National Wilms’ Tumor Study: A Progress Report

  • Giulio J. D’angio
  • J. Bruce Beckwith
  • Harry C. Bishop
  • Norman Breslow
  • Audrey E. Evans
  • Willard E. Goodwin
  • Lowell R. King
  • Lawrence K. Pickett
  • Lucius F. Sinks
  • Wataru W. Sutow
  • James A. Wolff

Abstract

Wilms’ tumor was virtually incurable before pediatric surgeons, notably Ladd1, perfected their surgical techniques. Steady improvements thereafter added radiation therapy2 and chemotherapy. The routine postoperative use of actinomycin-D, as reported by Farber3, produced a two-year survival rate of 81% in patients managed from the outset by an experienced team using combination therapy. Wolff and his colleagues4 demonstrated the value of cyclic actinomycin-D given over a prolonged period after operation, and otherss 5,6 showed that vincristine sulfate was effective in the management of these children.

Keywords

Tumor Study Vincristine Sulfate Pediatric Acute Leukemia Acute Leukemia Group Combine Patient Population 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    VIETTI, T. J., SULLIVAN, M. P., HAGGARD, M. E., HOLCOMB, T. M. and BERRY, D. H.: Vincristine sulfate and radiation therapy in metastatic Wilms’ tumor. Cancer, 25: 12, 1970.PubMedCrossRefGoogle Scholar
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    SCHNEIDER, M.: Renal embryoma. In: Progress in Radiation Therapy, edited by F. Buschke, Grune & Stratton, New York, 1958, p. 180.Google Scholar
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    D’ANGIO, G. J., BECKWITH, J. B., BISHOP, H. C., BRESLOW, N., EVANS, A. E., GOODWIN, W., KING, L. R., PICKETT, L. K., SINKS, L., SUTOW, W. W. and WOLFF, J. A.: The National Wilms’ Tumor Study: A Progress Report. Cancer. (In press)Google Scholar

Copyright information

© Ontario Cancer Treatment and Research Foundation 1973

Authors and Affiliations

  • Giulio J. D’angio
  • J. Bruce Beckwith
  • Harry C. Bishop
  • Norman Breslow
  • Audrey E. Evans
  • Willard E. Goodwin
  • Lowell R. King
  • Lawrence K. Pickett
  • Lucius F. Sinks
  • Wataru W. Sutow
  • James A. Wolff

There are no affiliations available

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