Controlled Clinical Trials in Leukemia in Children
To enable physicians to treat and study a greater number of patients with rare diseases in a shorter period through a predetermined method;
To enable rapid exploitation of animal model systems in man;
To shorten the time needed to test well-established drugs with respect to both dose and interval;
To facilitate the rapid exploration of the newer chemotherapeutic agents in the treatment of malignant disease.
KeywordsAcute Lymphocytic Leukemia Acute Leukemia Inducer Dose Animal Model System Pulse Dose
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