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Animal Scale-Up

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Pharmacology and Pharmacokinetics

Abstract

The title of this paper is freely adapted from a problem common to the art and science of chemical engineering: “plant scale-up” or “process scale-up.” A chemical reaction or a set of chemical reactions is discovered which leads to a potentially useful product. The basic chemistry is worked out, often in considerable detail, at the bench in glassware. It is necessary to design a plant which will make the product economically and consistent with other constraints imposed by society.

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Author information

Authors and Affiliations

  1. Biomedical Engineering and Instrumentation Branch Division of Research Services, National Institutes of Health, Bethesda, Maryland, USA

    Robert L. Dedrick

Authors
  1. Robert L. Dedrick
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Editor information

Editors and Affiliations

  1. Institute of Physiology and Medical Biophysics, University of Uppsala, Uppsala, Sweden

    Torsten Teorell

  2. Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA

    Torsten Teorell

  3. Biomedical Engineering and Instrumentation Branch Division of Research Services, National Institutes of Health, Bethesda, Maryland, USA

    Robert L. Dedrick

  4. Laboratory of Nutrition and Endocrinology, National Institute of Arthritis, Metabolism, and Digestive Diseases National Institutes of Health, Bethesda, Maryland, USA

    Peter G. Condliffe

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© 1972 Springer Science+Business Media New York

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Dedrick, R.L. (1972). Animal Scale-Up. In: Teorell, T., Dedrick, R.L., Condliffe, P.G. (eds) Pharmacology and Pharmacokinetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2055-5_7

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  • DOI: https://doi.org/10.1007/978-1-4684-2055-5_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2057-9

  • Online ISBN: 978-1-4684-2055-5

  • eBook Packages: Springer Book Archive

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