Pharmacokinetics and Pharmacodynamics of Acetazolamide in Relation to its Use in the Treatment of Glaucoma
Many speakers have alluded to the problem of describing the kinetics of the events at the drug receptor in relation to the time course of the physiological response. I would like to give an example of a drug action where it might be possible to unify the pharmacokinetic and the pharmacodynamic events.
KeywordsEnzyme Inhibition Carbonic Anhydrase Aqueous Humour Pharmacodynamic Event Carbonic Anhydrase Inhibitor
Unable to display preview. Download preview PDF.
- Lehman, B., Linnér, E., and Wistrand, P. J., 1969, The pharmacokinetics of acetazolamide in relation to its use in the treatment of glaucoma and to its effects as an inhibitor of carbonic anhydrases, in: Advances in the Biosciences Vol. 5, pp. 197–217 (G. Raspé, ed.), Pergamon Press, Oxford.Google Scholar