Neuronal Plasticity, Protein Conformation and Behavior

  • Holger Hydén


The influences of changes in behavior on the chemistry of different parts of the brain have been investigated. The results indicate the following working hypothesis: a sensory input causes an electrical field change around neurons in various regions of the brain. Ca increases and effects the translation of this electrical field change into conformational changes in brain specific protein of the cell membrane. The continuous protein network also reacts to Ca, modifying the membrane tension and facilitating the protein reaction. The pattern of surface protein and its conformational state could label and process valued information to neurons on electrical events where the final step involves the synapse.


Hippocampal Nerve Cell Nerve Cell Membrane Neuronal Plasticity Electrical Event Membrane Tension 
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Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • Holger Hydén
    • 1
  1. 1.Institute of Neurobiology Faculty of MedicineUniversity of GöteborgGöteborgSweden

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