Lithium pp 269-294 | Cite as

Prophylactic Lithium Maintenance Treatment in Recurrent Endogenous Affective Disorders

  • Mogens Schou


The demonstration of the prophylactic effect of lithium has been more difficult than the demonstration of its therapeutic effect. A convincing demonstration of the efficacy of this treatment was particularly important, because lithium has a relatively narrow therapeutic range. Prophylactic lithium treatment has been the subject of much debate, and a number of experimental designs were used to demonstrate its value. These studies have not only shed light on the clinical and pharmacological properties of the lithium ion; they have also provided new knowledge about the recurrent endogenous affective disorders.


Affective Disorder Depressive Episode Lithium Treatment Serum Lithium Concentration Index Episode 
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Copyright information

© Plenum Press, New York 1973

Authors and Affiliations

  • Mogens Schou
    • 1
    • 2
  1. 1.The Psychopharmacology Research UnitStatshospitaletRisskovDenmark
  2. 2.Aarhus UniversityAarhusDenmark

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