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Solvent Effects on Enzymes: Implications for Extraterrestrial Life

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Molecular Evolution

Abstract

Water plays many roles during the course of an enzymatic reaction. Its importance in maintaining the structural integrity of proteins has been emphasized repeatedly; water is also directly involved in many reactions as either a reactant or product. Additionally, there are more subtle effects of water influencing the ionization of charged groups, directing tertiary structure through interaction with hydrophobic and hydrophilic side-chains, binding at definite sites, and displacement during the course of reaction (1, 2).

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Heinrich, M.R. (1972). Solvent Effects on Enzymes: Implications for Extraterrestrial Life. In: Rohlfing, D.L., Oparin, A.I. (eds) Molecular Evolution. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2019-7_26

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  • DOI: https://doi.org/10.1007/978-1-4684-2019-7_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2021-0

  • Online ISBN: 978-1-4684-2019-7

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