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The Relationship of the (Na+ + K+)-Activated Enzyme System to Transport of Sodium and Potassium Across the Cell Membrane

  • J. C. Skou

Abstract

The energy-requiring, active, transport of sodium out and potassium into the cell seems to be due to the membrane bound (Na + K)-activated enzyme system.1–6 This system seems also to be involved in the Na: Na and K: K exchange which under certain conditions takes place across the cell membrane.4, 7 It has been named an enzyme system 1 since it not only catalyzes the hydrolysis of ATP but takes part in the reaction in the sense that the hydrolysis of ATP via this system seems to be translated into the vectorial movement of the cations against the electrochemical gradients, i.e. it seems to be identical with the transport system.

Keywords

Internal Solution Apparent Affinity Coupling Ratio Sodium Form Potassium Form 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Company Limited 1972

Authors and Affiliations

  • J. C. Skou
    • 1
  1. 1.Institute of PhysiologyUniversity of AarhusAarhus CDenmark

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