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Mechanisms of Androgen Induced Masculine Differentiation of the Rat Brain

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Hormones and Brain Function

Abstract

In order to put our more recent work in proper perspective, I would like first to review briefly the concept of sexual differentiation of the rat brain (for a more complete review see Gorski 1971a, b). Reproductive activity of the intact male rat is markedly different from that of the female. The adult male secretes androgen and forms mature spermatozoa essentially continuously. In addition, the male rat will display sexual behavior whenever presented with a receptive female. Although male sexual behavior is inhibited by a novel environment, once the experienced male adapts to the new environment of the testing cage, he will mate with the receptive female.

Original research by the author supported by Grant HD-01182 from the National Institute of Health and by the Ford Foundation.

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Authors and Affiliations

  1. Department of Anatomy and Brain Research Institute, UCLA School of Medicine, Los Angeles, Cal., USA

    K. A. Gorski

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  1. K. A. Gorski
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  1. University Medical School, Pécs, Hungary

    K. Lissák (Member of the Hungarian Academy of Sciences, Professor of Physiology) (Member of the Hungarian Academy of Sciences, Professor of Physiology)

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© 1973 Akadémiai Kiadó, Budapest, Hungary

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Gorski, K.A. (1973). Mechanisms of Androgen Induced Masculine Differentiation of the Rat Brain. In: Lissák, K. (eds) Hormones and Brain Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2007-4_3

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  • DOI: https://doi.org/10.1007/978-1-4684-2007-4_3

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-2009-8

  • Online ISBN: 978-1-4684-2007-4

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