Minor Components of tRNA
Characteristic structural elements of the tRNAs are the minor, rare, atypical, unusual, or accessory components which are derivatives of the four principal nucleic-acid bases. These compounds have attracted considerable attention for various reasons. To begin with, there was the problem of their origin: it was not understood how a tRNA, containing so many compounds of this type, can be synthesized by the complementary principle on a DNA consisting largely of four principal nucleotides. Investigators studying the primary structure of the nucleic acids showed great interest in these minor components, for they saw these compounds as convenient natural reference points making determination of the nucleotide sequence so much easier. Finally, research workers are still puzzled by the role of the minor components in tRNA.
KeywordsMinor Component Phosphodiester Bond Yeast tRNA tRNA Molecule Acceptor Activity
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