Advertisement

Evolutionary Modulation of Ribosomal RNA Synthesis in Oogenesis and Early Embryonic Development

  • Ronald R. Cowden

Abstract

One of the awesome things about Biological Sciences—particularly if it is capitalized—is its incredible breadth. As matters now stand, legitimate practitioners include all levels from the molecular biologist—who may never see the critter that delivers the juice he works with—to the man concerned with whole ecosystems and communities. Philosophically, and perhaps this is an important point, it also contains some extremes in orientation: on one hand the no-holds-barred experimentalist and on the other the descriptive museum-curator mentality. If the writer were to aim one criticism about the field as it exists today, it is that all of these elements have a contribution to make in the shaping of the profession and of the young people who have announced—with admittedly differing levels of commitment and sincerity—that they wish to place themselves in our hands to be trained as professionals. It is, in fact, a matter of record that communication between the diverse elements in this fascinating field has fallen into bad repair, and that excessive concentration by a department or research group on cellular biology to the exclusion of field biology has led to some forms of tubular vision that has hampered the visualization of biological problems in their total perspective. The writer was fortunate: he attended an essentially classically oriented undergraduate school, saw the mixture of these diverse elements in Cologne and Vienna as a graduate student, and spent his first years as a faculty member in one of the “most molecular” departments in the United States.

Keywords

Nucleolar Organizer Early Embryonic Development Cytochemical Study Helix Aspersa Swimming Larva 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alfert, M., “A cytochemical study of oogenesis and cleavage in the mouse.” J. Cellul Comp. Physiol 36, 381 (1950).CrossRefGoogle Scholar
  2. Austin, C. R., Nucleic acids associated with the nucleoli of living segmented rat eggs. Exp. Cell. Res. 4, 249 (1953).CrossRefGoogle Scholar
  3. Block, D. P., and H.C.Y. Hew, “Changes in nuclear histones during fertilization and early development in the pulmonate snail.” Helix aspersa. J. Biophys. Biochem Cytol. 8, 69 (1960).CrossRefGoogle Scholar
  4. Brown, D. D., and J. B. Gurdon, “Absence of ribosomal RNA synthesis in the anucleolate mutant of Xenopus laevis.” Proc. Nat. Acad. Sci. (U.S.A.) 51, 139 (1964).CrossRefGoogle Scholar
  5. Burmann, W., “Der Nukleolus als lebenswichtiger Bestandteil des Zellkernes.” Chromosoma 11, 262 (1960).Google Scholar
  6. Cowden, R. R., “A cytochemical investigation of oogenesis and development to the swimming larval stage in the chiton.” Chiton tuberculatum L. Biol. Bull. 120, 313 (1961).Google Scholar
  7. Cowden, R. R., “RNA and protein distribution during the development of axial mesodermal structures in the ascidian.” Clavelina picta. Roux’ Archiv. Entwicklungsmech. 154, 526 (1968).CrossRefGoogle Scholar
  8. Cowden, R. R., “Cytochemical studies of embryonic development to metamorphosis in the gymnoblastic hydroid.” Pennaria tiarella. Acta Emb. Morph. Exp. 8, 221 (1965a).Google Scholar
  9. Cowden, R. R., “Cytochemical studies on cytoplasmic RNA-associated basic proteins in oocytes, somatic cells and ribosomes.” Histochemie 6, 226 (1965b).CrossRefGoogle Scholar
  10. Cowden, R. R., and C. L. Markert, “A cytochemical study of the development of Ascidia nigra.” Acta Emb. Morph. Exp. 4, 142 (1961).Google Scholar
  11. Mancuso, V., “Gli acidi nucleici nell’uovo in silvoppo di Ciona intestinalis.” Acta Emb. Morph. Exp. 2, 151 (1959).Google Scholar
  12. Markert, C. O., and R. R. Cowden, “Comparative responses of regulative and determinate embryos to metabolic inhibitors.” J. Exp. Zool 160, 37 (1965).CrossRefGoogle Scholar
  13. Mergener, H., Die Ei—und Embryonalentwicklung von Eudendrium rasemosum Cavolini. Zool. Jb.; Abt. Anat u-Ont. Tiere 76, 63 (1957).Google Scholar
  14. Mintz, B., “Synthetic processes and early development in the mammalian egg.” J. Exp. Zool. 157, 85 (1964).CrossRefGoogle Scholar
  15. Raven, C. P., OOgensis: The Storage of Developmental Information. Pergamon Press, New York (1958).Google Scholar
  16. Smith, K. D., “Genetic control of macromolecular synthesis during development of an ascidian: Ascidia nigra.” J. Exp. Zool. 164, 393 (1967).CrossRefGoogle Scholar
  17. Ubbels, G. A., A cytochemical Study of Oogenesis in the Pond Snail, Limaea saginalis. Bronder-Offset, Rotterdam (1968).Google Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • Ronald R. Cowden
    • 1
  1. 1.University of DenverUSA

Personalised recommendations