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Biochemical Neurological Disease in Children

  • L. I. Woolf

Abstract

Biochemical disease involves a departure from the normal in some body component, e.g. an enzyme, a structural protein or a membrane transport mechanism. Some biochemical diseases are almost entirely environmental in origin, e.g. lead encephalopathy, but at present attention is largely directed to genetically determined conditions-the inborn errors of metabolism and other molecular diseases. In some cases it is the interaction between genotype and external environment which brings about the signs and symptoms, in others, such as the gangliosidoses, no modification of the external environment can appreciably alter the course of the disease.

Keywords

Amino Acid Metabolism Inborn Error Lipoic Acid Pyruvate Carboxylase Homo Cystinuria 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Plenum Publishing Company Ltd. 1972

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  • L. I. Woolf

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