Technology of Induction of Cancer in Rat with Pulse-Doses of Homogenized Hydrocarbons
The research began with the work of a thoughful and colorful surgeon, Percivall Pott (1713–1788), and his investigation(1) of cancer of the scrotum: “there is a disease as peculiar to a certain set of people, which has not, at least to my knowledge, been publicly noticed; I mean the chimney-sweeper’s cancer. It is a disease which always makes its first attack on, and its first appearance in, the inferior part of the scrotum; where it produces a superficial, painful, ragged, ill-looking sore, with hard and rising edges: the trade call it the soot-wart. I never saw it under the age of puberty”.
KeywordsMammary Cancer Lipid Emulsion Single Feeding Carcinogenic Polycyclic Aromatic Hydrocarbon Carcinogenic Hydrocarbon
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- 1.Pott, P. Cancer scroti. The chirurgical works of Percivall Pott. London, Wood and Innes, 3: 174, 1808.Google Scholar
- 2.Yamagiwa, K., and Ichikawa, K. Experimentelle Studie über die Pathogenese der Epithelialgeschwülste. Mitt. Fak. K. Japan. Univ. Tokyo 15: 295, 1916.Google Scholar