Liquid Chromatography—The Background

  • S. G. Perry
  • R. Amos
  • P. I. Brewer


Liquid chromatography has an impressive history, stretching back into the 19th century, which has been well documented elsewhere(1). As an indispensable technique for the separation and analysis of organic substances it has made enormous strides in the past decade or so. Prior to 1958 column chromatography was conducted with comparatively large samples separated in, often short, almost invariably wide-bore, columns through which the developing liquid percolated under gravity. Thin-layer techniques were unknown outside a small group of workers(2), although paper chromatography was widely practiced.


Mobile Phase Stationary Phase Theoretical Plate Adsorption Chromatography Partition Chromatography 
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  1. 1.
    Heftmann, E. (ed.), Chromatography ,Reinhold, New York (1967).Google Scholar
  2. 2.
    Pelick, N., Bolliger, H.R., and Mangold, H.K., The history of thin-layer chromatography, Advan. Chromatog. 3, 85 (1966).Google Scholar
  3. 3.
    Stahl, E. (ed.), Thin Layer Chromatography ,Springer-Verlag, Berlin (1969).Google Scholar
  4. 4.
    Webster, P.V., Wilson, J.N., and Franks, M.C., J. Inst. Pet. 56, 50 (1970).Google Scholar

Further Reading

  1. Authoritative reviews on various aspects of liquid chromatography are to be found in two regular publications:Google Scholar
  2. Chromatographic Reviews ,Lederer, M. (ed.), Elsevier, Amsterdam.Google Scholar
  3. Advances in Chromatography ,Giddings, J.C., and Keller, R.A. (eds.), Marcel Dekker, New York.Google Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • S. G. Perry
    • 1
  • R. Amos
    • 1
  • P. I. Brewer
    • 1
  1. 1.Esso Research CentreEsso Petroleum Company, LimitedAbingdon, BerkshireEngland

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