Induction of the Hepatic Amino Acid Transport System and Tyrosine Aminotransferase in Rats on Controlled Feeding Schedules

  • David F. Scott
  • Fred R. Butcher
  • Robert D. Reynolds
  • Van R. Potter


In considering the “biochemical responses to environmental stress” in mammalian organisms it is appropriate to examine the adaptive changes that occur in the liver. This organ is not only concerned with the detoxification of toxic environmental hazards but it is also primarily responsible for maintaining homeostasis in the internal environment despite uneven variations in the time of food ingestion and in the proportions of dietary carbohydrate, protein and fat. The concept of environmental stress is coupled with the concept of physiological adaptation and both have been given definitions that range from the idea that stress is something harmful to the idea that some stress and adaptation is part of everyday living and that indeed we have to inquire about the range of stress levels that might be regarded as part of an “optimum environment” (see Aschoff, 1967, The Handbook of Physiology, Sect. 4 and discussions by Potter, 1969, 1970).


Amino Acid Transport Quinolinic Acid Tyrosine Aminotransferase Amino Acid Transport System Aminoisobutyric Acid 
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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • David F. Scott
    • 1
  • Fred R. Butcher
    • 1
  • Robert D. Reynolds
    • 1
  • Van R. Potter
    • 1
  1. 1.McArdle LaboratoryUniversity of Wisconsin Medical SchoolMadisonUSA

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