Assessing Loss Rates in the Preimplantation Stages of Gestation
Assessing safety of preimplantation genetics procedures requires a clear understanding of the natural history of pregnancy losses. Two aspects in particular will be addressed here - 1) What is the natural history of losses, both in vivo as well as in vitro? 2) What potential confounding variables need to be taken into account in order to judge loss rates in the four — to eight — cell embryo or in the blastocyst subjected to manipulation?
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