Porphyrins in Diseases Other than the Porphyrias
Disturbances of heme biosynthesis and porphyrin metabolism occur in a variety of acquired and inherited diseases in addition to the hereditary porphyrias. Studies of porphyrin metabolism in these conditions provide a useful insight into the underlying disease process as well as being of clinical value in both diagnosing and assessing the severity of the disorder. The abnormal porphyrin metabolism identified in tumor cells has been employed as an aid to therapy.
KeywordsHeme Biosynthesis Sideroblastic Anemia Erythrocyte Protoporphyrin Porphyrin Metabolism Uroporphyrinogen Decarboxylase
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