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HDL Binding to Human Adipocyte Plasma Membranes: Regional Variation in Omental and Subcutaneous Depots

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Lipoprotein Deficiency Syndromes

Part of the book series: Advances in Experimetal Medicine and Biology ((AEMB,volume 201))

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Abstract

Human adipose tissue contains one of the largest pools of exchangeable cholesterol in the body, accounting for about 25 percent of total body cholesterol in normal man (1,2). This adipose cholesterol pool is much expanded in obesity and in the massively obese state, well over half of total body cholesterol can be found in the fat tissue (1,2). Obesity is also commonly associated with a number of lipoprotein abnormalities. Increased synthesis and/or turnover of LDL (3) and VLDL (4,5) have been reported. In addition, HDL-cholesterol in plasma is significantly reduced (6–13) and has been attributed primarily to a decrease in the HDL2 subfraction (7).

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Authors and Affiliations

  1. Department of Medicine and Institute of Medical Science, University of Toronto and Division of Endocrinology and Metabolism, Toronto General Hospital, Toronto, Ontario, Canada, M5S 1A8

    Bessie Fong, Andrew Salter, Jose Jimenez, Jean-Pierre Despres & Aubie Angel

Authors
  1. Bessie Fong
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  2. Andrew Salter
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  3. Jose Jimenez
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  4. Jean-Pierre Despres
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  5. Aubie Angel
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Editor information

Editors and Affiliations

  1. Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada

    Aubie Angel

  2. Shaughnessy Hospital, University of British Columbia, Vancouver, British Columbia, Canada

    Jiri Frohlich

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© 1986 Springer Science+Business Media New York

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Fong, B., Salter, A., Jimenez, J., Despres, JP., Angel, A. (1986). HDL Binding to Human Adipocyte Plasma Membranes: Regional Variation in Omental and Subcutaneous Depots. In: Angel, A., Frohlich, J. (eds) Lipoprotein Deficiency Syndromes. Advances in Experimetal Medicine and Biology, vol 201. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1262-8_6

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  • DOI: https://doi.org/10.1007/978-1-4684-1262-8_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1264-2

  • Online ISBN: 978-1-4684-1262-8

  • eBook Packages: Springer Book Archive

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