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Transmitters and Receptors in the Basal Ganglia

  • Chapter
The Basal Ganglia

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 27))

Abstract

This chapter surveys the neurotransmitters and their receptors within the neostriatum (caudate-putamen, NS), globus pallidus (GP) and substantia nigra (SN), but is deliberately biased towards those transmitters involved in the principal input and output pathways of the basal ganglia in an attempt to relate neuronal circuitry to function. Where appropriate, behavioural data have also been presented and reference has been made to the abnormal movement disorders affecting basal ganglia function. Morphological evidence for the relevant pathways and connections can be found elsewhere within this volume. No attempt has been made to consider the peptide transmitters, neurotensin, somatostatin, TRH, angiotensin, cholecystokinin and the opiates, which are found in the basal ganglia, but whose involvement in motor function has not been well established. Whereas species differences may be of considerable importance in any anatomical review, there is insufficient evidence pertaining to the variation across species of pharmacological and neurochemical data, and thus attempts have generally not been made to nominate the animal species employed. The present article will not discuss the ventral striatum (nucleus accumbens septi), whose connections are less well defined, but these have been dealt with elsewhere (Fonnum and Walaas, 1979; Heimer and Van Hoesen, 1979).

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Authors and Affiliations

  1. Clinical Pharmacology and Therapeutics Austin Hospital, University of Melbourne, 3084, Heidelberg, Victoria, Australia

    Philip M. Beart

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  1. Philip M. Beart
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  1. University of Melbourne, Parkville, Victoria, Australia

    John S. McKenzie , Robert E. Kemm  & Lynette N. Wilcock ,  & 

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© 1984 Plenum Press, New York

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Beart, P.M. (1984). Transmitters and Receptors in the Basal Ganglia. In: McKenzie, J.S., Kemm, R.E., Wilcock, L.N. (eds) The Basal Ganglia. Advances in Behavioral Biology, vol 27. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1212-3_13

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  • DOI: https://doi.org/10.1007/978-1-4684-1212-3_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1214-7

  • Online ISBN: 978-1-4684-1212-3

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