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Glutamate and Glutamine Transport in Cultured Neuronal and Glial Cells

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Neurotransmitter Interaction and Compartmentation

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 48))

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Abstract

Glial cells are thought to be the main source of glutamine in the CNS, because of their high content in glutamine synthetase (Norenberg and Martinez-Hernandez, 1979). If glutamine is a precursor of GABA in Gabaergic neurons, one would expect a flow of glial glutamine towards the neurons. Neuronal and glial cells have been attributed different metabolic compartments which are in relation one with the other through the transfer of glutamate, GABA or glutamine in both directions (Benjamin and Quastel, 1972 ; Bradford et al., 1978 ; Hamberger et al., 1979).

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© 1982 Springer Science+Business Media New York

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Borg, J., Ramaharobandro, N., Mark, J. (1982). Glutamate and Glutamine Transport in Cultured Neuronal and Glial Cells. In: Bradford, H.F. (eds) Neurotransmitter Interaction and Compartmentation. NATO Advanced Study Institutes Series, vol 48. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-1140-9_24

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  • DOI: https://doi.org/10.1007/978-1-4684-1140-9_24

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-1142-3

  • Online ISBN: 978-1-4684-1140-9

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